Semen may interfere with HIV microbicides

Published: November 12, 2014

Yahoo News
Original Article:  yhoo.it/1oSdops

Semen appears to interfere with microbicide gels to prevent HIV, possibly explaining why they work in the lab but not in real-life situations, scientists said Wednesday.

Protein fragments found in semen hamper the work of microbicides applied to the vagina, said the report in the journal Science Translational Medicine.

Known as amyloid fibrils, these particles in semen "act like glue to attach HIV particles to the cell surface and boost viral infectivity," said the study led by scientists at the University of California, San Francisco and the University of Ulm in Germany.

"This effect overpowers the anti-HIV activity of microbicides."

Full text of article available at link below:  yhoo.it/1oSdops

 

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