HIV-positive men who have sex with men (MSM) acquire new anal infections with cancer-associated strains of human papillomavirus (HPV) at high rates, aidsmap reports. Publishing their findings in the journal AIDS, investigators in San Francisco conducted a prospective study of MSM whom they recruited between 1998 and 2000 and followed for at least two years.
Published: April 3, 2014
In addition to responding to questions about their recent sexual behavior, the study participants received swabs every six months to detect anal HPV infection. Seventy-five percent reported having anal or genital warts in the past, and 92 percent had some form of anal HPV at the beginning of the study. Seventy-eight percent of the men had low- or high-grade precancerous anal cell changes at the study’s outset.
The annual rate of new anal infections—also known as the incidence—with any type of HPV was 21.3 per 100 person-years, while the incidence for cancer-linked HPV strains was 13.3 per 100 person-years. The two types of HPV most associated with anal cancer were also the most commonly acquired each year: HPV 18 had an incidence rate of 3.7 per 100 person-years, while HPV 16’s rate was 3.5 per 100 person-years.
Full text of article available at link below –