Changes of HIV and syphilis infection among men who have sex with men in Beijing China
Background: Little is known about the dynamic of infection rates of human immunodeficiency virus (HIV) and syphilis among men who have sex with men (MSM) in China.
Methods: A cross-sectional survey of more than 500 MSM was conducted in 2005 and 2006. A prospective cohort of 515 HIV-seronegative MSM was followed up every 3 months starting from 2006. Questionnaire with interviews were conducted to collect seroconversion and risk behaviors information.
Results: HIV and syphilis prevalence was increased from 3.2% and 11.2% in 2005, to 4.8% and 19.8% in 2006, respectively. HIV infection was significantly associated with syphilis seropositivity in the final logistic regression. In risk behavior, 46% had >10 lifetime male sex partners and 52% reported having sex with women. Consistent condom use with primary and non-primary male sex partners was 57% and 60% in the last month, respectively. Among them, 2% reported using Ecstasy or Ketamine in the past 3 months, 66% are not Beijing residences. 88% were retained during the 6-month follow-up survey. The average incidence rate was 1.27 and 11.86 per 100 person-years for HIV and syphilis respectively. Multiple HIV-1 clades were detected in the group including the major ones such as B (41.9%) and CRF01_AE( 30.2%) as well as minor ones including CRFs; CRF01_AE and CRF07_BC), and a variety of unique recombinant forms (URFs).
Conclusions: High mobility, multiple sexual partners, and high prevalence of unprotected sex behaviors and high syphilis and relatively high HIV infection suggest a potential rapid spread of HIV in Chinese MSM and then from MSM to female partners.
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