AVAC Report: Turning the Page

Published: July 1, 2010

Table of Contents

What Belongs in the Next Chapter…..2
A letter from the Executive Director….. 2
AVAC Report 2010 Dedication….. 6
AVAC’s Top Recommendations for 2010 and Beyond….. 7
Status Report: An update on last year’s recommendations….. 8
Chapter One “Proof of Concept” and its Consequences: Making sense of the post-RV144 world…..9
Basics of RV144….. 11
RV144 Results….. 12
RV144 Trial Locations….. 22
RV144: A Brief History …..25
Moment of Truth: Action and accountability for the Enterprise….. 18
Chapter Two The Thai Way Forward: What comes after the largest AIDS vaccine trial in the world?…..19
Chapter Three Data and Materials: A “to-do” list for the future….. 29
Intellectual Property and Access: Revisiting our 2005 recommendations….. 32
Data and Materials: Defining the terms….. 38
Chapter Four Trials and Trial Design: Where does prevention research
go from here?…..39
ARV-based Prevention Update….. 48
Conclusion Speak with One Voice, Work Towards One Goal….. 50
AVAC’s Global Partners in Prevention Research Advocacy….. 54
About AVAC….. 56
Boxes, Figures and Tables
Turning the Page: The need to diversify funding sources….. 13
Turning the Page: Applying lessons from recent trials….. 27
Turning the Page: Engaging new talent in the search for an AIDS vaccine….. 35
Turning the Page: Innovation in prevention packages….. 43
Adaptive Trials versus Classical Trials: A highly-optimistic comparison 55
AVAC’s Web-based Resources….. 17
What is Community Engagement?….. 23
Learning our Lessons on Community Engagement: Another trial, another lesson?…..26
Sharing the Search for Clues: Step and RV144 post-trial analysis….. 37
Sticking to It: Keeping up with the challenges of adherence….. 45
Ongoing ARV-based Prevention Trials (as of June 2010)….. 46
The Global AIDS Response: Five Current Myths Versus Current Realities….. 52

Full text of report available at link below –

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